NethoLabs

Towards New Frontiers in Neuroscience

The rapid technological advancements of the 21st century offer unprecedented opportunities to study the brain. By merging neuro-technologies with artificial intelligence (AI), we can pioneer a new class of research: longitudinal neuroethology. This paradigm allows us to study the brain during innate and instinctive behaviors over extended periods, from weeks to years.

Neuroethology for Psychiatric Disease Research

Complex brain disorders like schizophrenia (SZ) manifest via cognitive symptoms, such as impairments in the sense of agency (SoA) over thoughts and actions. Understanding how the brain computes SoA during natural behaviors can unveil new insights into the anatomical and functional circuits involved in SZ, which are often elusive in genetic studies alone that can only explain a few percent of SZ occurence.

Whole-Brain-Emulation (WBE): Digitized Rodent Models

Longintudinal neuroethology frameworks will increasingly enable the generation of platforms for whole-brain dynamical models such as whole-brain-emulators (WBE): i.e., measuring, modeling, and emulating biological nervous systems in digital environments. WBE paradigms are theoretically and experimentally sound and can provide a new way to conceptualize neural dynamics from the whole-organism perspective. Emulators - or digital models of animals - can advance our scientific knowledge while decreasing the burden on research animals.